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\u5728\u5316\u5b66\u7684\u5e7f\u9614\u5929\u5730\u4e2d\uff0c\u5341\u56db\u70f7\u57fa\u4e09\u7532\u57fa\u6c2f\u5316\u94f5\uff08C14TAC\uff09\u5b9b\u5982\u4e00\u9897\u7480\u74a8\u7684\u660e\u661f\uff0c\u4ee5\u5176\u72ec\u7279\u7684\u5316\u5b66\u6027\u8d28\u548c\u5e7f\u6cdb\u7684\u5e94\u7528\u9886\u57df\uff0c\u5438\u5f15\u7740\u65e0\u6570\u79d1\u7814\u4eba\u5458\u548c\u4f01\u4e1a\u7684\u76ee\u5149\u3002\u672c\u6587\u5c06\u6df1\u5165\u5256\u6790 C14TAC \u7684\u6838\u5fc3\u7279\u6027\u4e0e\u5e94\u7528\uff0c\u5e26\u60a8\u9886\u7565\u5b83\u7684\u72ec\u7279\u9b45\u529b\u3002<\/p>\n\n\n\n

\u57fa\u7840\u7279\u6027\u6982\u89c8<\/strong><\/p>\n\n\n\n

C14TAC \u7684\u5206\u5b50\u91cf\u4e3a 279.93 g\/mol\uff0c\u5728 25\u2103 \u65f6\uff0c\u5176\u4e34\u754c\u80f6\u675f\u6d53\u5ea6\uff08CMC\uff09\u4ecb\u4e8e 3.5 – 4.2 mM \u4e4b\u95f4\uff0c\u5f62\u6210\u7684\u80f6\u675f\u5c3a\u5bf8\u7ea6\u4e3a 3.8\u00b10.5 nm\u3002\u5b83\u62e5\u6709 28\u2103 \u7684 Krafft \u70b9\uff0c0.1% \u6eb6\u6db2\u7684\u8868\u9762\u5f20\u529b\u4e3a 32.5 mN\/m\u3002\u8fd9\u4e9b\u57fa\u7840\u7279\u6027\uff0c\u4e3a C14TAC \u5728\u5404\u4e2a\u9886\u57df\u7684\u51fa\u8272\u8868\u73b0\u5960\u5b9a\u4e86\u575a\u5b9e\u57fa\u7840\u3002<\/p>\n\n\n\n

\u516d\u5927\u6838\u5fc3\u4f5c\u7528\uff0c\u5404\u9886\u98ce\u9a9a<\/strong><\/p>\n\n\n\n

1\u3001\u6297\u83cc\u5148\u950b\uff0c\u5b88\u62a4\u5065\u5eb7\u9632\u7ebf<\/strong><\/p>\n\n\n\n

C14TAC \u51ed\u501f\u9633\u79bb\u5b50\u5438\u9644\u7ec6\u83cc\u7ec6\u80de\u819c\uff0c\u8fdb\u800c\u5bfc\u81f4\u819c\u7ed3\u6784\u5d29\u89e3\uff0c\u4f7f\u80de\u5185\u7269\u8d28\u6cc4\u6f0f\uff0c\u53d1\u6325\u5f3a\u5927\u7684\u6297\u83cc\u4f5c\u7528\u3002\u5728\u533b\u7528\u6d88\u6bd2\u5242\u9886\u57df\uff0c\u4ec5\u9700 0.05%-0.2% \u7684\u6d53\u5ea6\uff0c\u5c31\u80fd\u6709\u6548\u6740\u83cc\uff0c\u4e3a\u533b\u7597\u73af\u5883\u7b51\u7262\u5b89\u5168\u9632\u7ebf\u3002\u5728\u9690\u5f62\u773c\u955c\u62a4\u7406\u6db2\u4e2d\uff0c\u4e0e\u805a\u5b63\u94f5\u76d0 – 1 \u590d\u914d\u4f7f\u7528\uff0c\u4e3a\u773c\u775b\u5065\u5eb7\u4fdd\u9a7e\u62a4\u822a\u3002\u66f4\u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0c\u7528\u4e8e\u521b\u9762\u6577\u6599\u65f6\uff0c24 \u5c0f\u65f6\u6291\u83cc\u7387\u8d85\u8fc7 99.9%\uff0c\u4e3a\u4f24\u53e3\u6108\u5408\u521b\u9020\u65e0\u83cc\u73af\u5883\u3002<\/p>\n\n\n\n

2\u3001\u6297\u9759\u7535\u4e13\u5bb6\uff0c\u89e3\u51b3\u9759\u7535\u56f0\u6270<\/strong><\/p>\n\n\n\n

\u9759\u7535\u95ee\u9898\u5728\u7eba\u7ec7\u548c\u5851\u6599\u884c\u4e1a\u4e00\u76f4\u4ee4\u4eba\u5934\u75bc\uff0c\u800c C14TAC \u5374\u80fd\u8f7b\u677e\u5316\u89e3\u3002\u5b83\u80fd\u8ba9\u6da4\u7eb6\u7ec7\u7269\u8868\u9762\u7535\u963b\u4ece 10\u00b9\u00b2\u03a9 \u964d\u81f3 10\u2078\u03a9\uff0c\u5373\u4f7f\u8010\u6c34\u6d17 5 \u6b21\u540e\uff0c\u4ecd\u80fd\u4fdd\u6301 85% \u7684\u6297\u9759\u7535\u6548\u679c\u3002\u5728\u6d17\u53d1\u6c34\u4e2d\u6dfb\u52a0 0.3%-0.8% \u7684 C14TAC\uff0c\u6216\u5728\u5851\u6599\u6bcd\u7c92\u4e2d\u6dfb\u52a0 1.2 – 1.5% \u7684\u6bd4\u4f8b\uff0c\u5c31\u80fd\u6709\u6548\u89e3\u51b3\u9759\u7535\u95ee\u9898\uff0c\u8ba9\u751f\u6d3b\u548c\u751f\u4ea7\u66f4\u52a0\u987a\u7545\u3002<\/p>\n\n\n\n

3\u3001\u76f8\u8f6c\u79fb\u50ac\u5316\u5242\uff0c\u52a0\u901f\u5316\u5b66\u53cd\u5e94\u8fdb\u7a0b<\/strong><\/p>\n\n\n\n

\u5728\u5316\u5b66\u5408\u6210\u9886\u57df\uff0cC14TAC \u4f5c\u4e3a\u76f8\u8f6c\u79fb\u50ac\u5316\u5242\uff0c\u8868\u73b0\u5c24\u4e3a\u51fa\u8272\u3002\u5728\u785d\u5316\u53cd\u5e94\u4e2d\uff0c\u5b83\u80fd\u4f7f\u53cd\u5e94\u901f\u7387\u63d0\u5347 6 – 8 \u500d\u3002\u5728\u6c34 \/ \u6cb9\u4e24\u76f8\u4f53\u7cfb\u4e2d\uff0c\u7528\u91cf\u4e3a\u53cd\u5e94\u7269\u8d28\u91cf\u7684 0.5%-1.2% \u65f6\uff0c\u5c31\u80fd\u53d1\u6325\u51fa\u8272\u7684\u50ac\u5316\u6548\u679c\uff0c\u5927\u5927\u63d0\u9ad8\u4e86\u5316\u5b66\u53cd\u5e94\u7684\u6548\u7387\u3002<\/p>\n\n\n\n

4\u3001\u7eb3\u7c73\u6750\u6599\u6a21\u677f\uff0c\u7cbe\u51c6\u8c03\u63a7\u7eb3\u7c73\u7ed3\u6784<\/strong><\/p>\n\n\n\n

\u968f\u7740\u7eb3\u7c73\u6280\u672f\u7684\u98de\u901f\u53d1\u5c55\uff0cC14TAC \u5728\u7eb3\u7c73\u6750\u6599\u5408\u6210\u4e2d\u626e\u6f14\u7740\u91cd\u8981\u89d2\u8272\u3002\u5b83\u53ef\u4ee5\u8c03\u63a7\u4ecb\u5b54\u4e8c\u6c27\u5316\u7845\u7684\u5b54\u5f84\u5728 2 – 8nm \u8303\u56f4\u5185\uff0c\u8fd8\u80fd\u8c03\u8282\u91d1\u7eb3\u7c73\u68d2\u7684\u957f\u5f84\u6bd4\uff082:1 \u81f3 8:1\uff09\u3002\u901a\u8fc7\u63a7\u5236\u6d53\u5ea6\u68af\u5ea6\u5728 0.5 – 5 mM\uff0c\u4ee5\u53ca pH \u8303\u56f4\u5728 6.5 – 8.5\uff0c\u5c31\u80fd\u5b9e\u73b0\u5bf9\u7eb3\u7c73\u6750\u6599\u7684\u7cbe\u51c6\u5408\u6210\uff0c\u4e3a\u7eb3\u7c73\u6750\u6599\u7684\u6027\u80fd\u4f18\u5316\u63d0\u4f9b\u4e86\u6709\u529b\u652f\u6301\u3002<\/p>\n\n\n\n

5\u3001\u77f3\u6cb9\u5f00\u91c7\u52a9\u5242\uff0c\u63d0\u5347\u5f00\u91c7\u6548\u7387<\/strong><\/p>\n\n\n\n

\u5728\u77f3\u6cb9\u5f00\u91c7\u884c\u4e1a\uff0cC14TAC \u4e5f\u5c55\u73b0\u51fa\u4e86\u4e0d\u4fd7\u7684\u5b9e\u529b\u3002\u5728\u6cb9\u7530\u5e94\u7528\u4e2d\uff0c\u5b83\u7684\u7f13\u8680\u6548\u7387\u8d85\u8fc7 92%\uff0860\u2103, 5% NaCl \u6eb6\u6db2\uff09\uff0c\u8fd8\u80fd\u964d\u4f4e\u7a20\u6cb9\u7c98\u5ea6 35%-40%\u3002\u4e0e OP – 10 \u590d\u914d\uff083:1 \u6bd4\u4f8b\uff09\u4f7f\u7528\uff0c\u6d53\u5ea6\u4e3a 0.05%-0.15% \u65f6\uff0c\u6548\u679c\u66f4\u4f73\uff0c\u4e3a\u77f3\u6cb9\u5f00\u91c7\u7684\u9ad8\u6548\u8fdb\u884c\u63d0\u4f9b\u4e86\u6709\u529b\u4fdd\u969c\u3002<\/p>\n\n\n\n

6\u3001\u5206\u6790\u5316\u5b66\u8bd5\u5242\uff0c\u52a9\u529b\u79d1\u5b66\u7814\u7a76<\/strong><\/p>\n\n\n\n

\u5728\u5206\u6790\u5316\u5b66\u9886\u57df\uff0cC14TAC \u4e5f\u6709\u7740\u5e7f\u6cdb\u7684\u5e94\u7528\u3002\u5b83\u53ef\u4f5c\u4e3a\u8367\u5149\u63a2\u9488\u8f7d\u4f53\uff0c\u4f7f\u8298\u63a2\u9488\u589e\u654f 8 – 10 \u500d\uff0c\u8fd8\u80fd\u8c03\u8282\u86cb\u767d\u8d28\u7535\u6cf3\u8fc1\u79fb\u7387\u3002\u5728\u6bdb\u7ec6\u7ba1\u7535\u6cf3\u4e2d\uff0c\u5de5\u4f5c\u6d53\u5ea6\u4e3a 15 – 25 mM\uff1b\u5728\u5149\u8c31\u5206\u6790\u4e2d\uff0c\u5de5\u4f5c\u6d53\u5ea6\u4e3a 0.1 – 0.5 mM\uff0c\u4e3a\u79d1\u5b66\u7814\u7a76\u63d0\u4f9b\u4e86\u6709\u529b\u7684\u5de5\u5177\u3002<\/p>\n\n\n\n

\u5b89\u5168\u987b\u77e5\uff0c\u4f7f\u7528\u65e0\u5fe7<\/strong><\/p>\n\n\n\n

\u5728\u4eab\u53d7 C14TAC \u5e26\u6765\u7684\u8bf8\u591a\u4fbf\u5229\u7684\u540c\u65f6\uff0c\u6211\u4eec\u4e5f\u9700\u8981\u6ce8\u610f\u4e00\u4e9b\u5b89\u5168\u4e8b\u9879\u3002\u9996\u5148\uff0c\u8981\u907f\u514d\u5b83\u4e0e\u9634\u79bb\u5b50\u8868\u9762\u6d3b\u6027\u5242\u76f4\u63a5\u6df7\u5408\uff0c\u5426\u5219\u4f1a\u4ea7\u751f\u6c89\u6dc0\uff0c\u5f71\u54cd\u4f7f\u7528\u6548\u679c\u3002\u5982\u679c\u4e0d\u5c0f\u5fc3\u773c\u90e8\u63a5\u89e6\uff0c\u9700\u7acb\u5373\u7528\u751f\u7406\u76d0\u6c34\u51b2\u6d17 15 \u5206\u949f\uff0c\u4ee5\u51cf\u8f7b\u4f24\u5bb3\u3002\u5b58\u50a8\u65f6\uff0c\u8981\u5bc6\u5c01\u907f\u5149\u4fdd\u5b58\uff0c\u8fd9\u6837\u5b83\u7684\u6709\u6548\u671f\u53ef\u8fbe 24 \u4e2a\u6708\u3002\u5373\u4f7f\u51fa\u73b0\u7ed3\u5757\uff0c\u653e\u5728 60\u2103 \u6c34\u6d74\u4e2d\u590d\u6eb6\uff0c\u4e5f\u4e0d\u4f1a\u5f71\u54cd\u5176\u6027\u80fd\uff0c\u4f9d\u7136\u53ef\u4ee5\u6b63\u5e38\u4f7f\u7528\u3002<\/p>\n\n\n\n

\u68c0\u6d4b\u65b9\u6cd5\u4f18\u5316\uff0c\u7cbe\u51c6\u6d4b\u91cf<\/strong><\/p>\n\n\n\n

\u4e3a\u4e86\u66f4\u597d\u5730\u4e86\u89e3\u548c\u5229\u7528 C14TAC\uff0c\u7cbe\u51c6\u7684\u68c0\u6d4b\u65b9\u6cd5\u81f3\u5173\u91cd\u8981\u3002\u5728\u68c0\u6d4b C14TAC \u65f6\uff0c\u7535\u5bfc\u7387\u6cd5\u68c0\u6d4b DTAC \u7684 CMC \u5efa\u8bae\u6d53\u5ea6\u8303\u56f4\u4e3a 1 – 10mM\u3002\u8367\u5149\u6cd5\u9009\u7528\u5c3c\u7f57\u7ea2\u63a2\u9488\u66f4\u654f\u611f\uff0c\u6fc0\u53d1\u6ce2\u957f\u4e3a 530nm\u3002\u52a8\u6001\u5149\u6563\u5c04\u68c0\u6d4b\u65f6\uff0c\u9700\u9884\u70ed\u81f3 30\u2103 \u4ee5\u4e0a\uff0c\u8d85\u8fc7 Krafft \u70b9\uff0c\u4ee5\u83b7\u5f97\u66f4\u51c6\u786e\u7684\u68c0\u6d4b\u7ed3\u679c\u3002<\/p>\n\n\n\n

C14TAC \u51ed\u501f\u5176\u72ec\u7279\u7684\u7279\u6027\u548c\u591a\u6837\u7684\u5e94\u7528\uff0c\u5728\u5316\u5b66\u9886\u57df\u4e2d\u5c55\u73b0\u51fa\u65e0\u9650\u53ef\u80fd\u3002\u65e0\u8bba\u662f\u6297\u83cc\u3001\u6297\u9759\u7535\uff0c\u8fd8\u662f\u4f5c\u4e3a\u50ac\u5316\u5242\u3001\u6a21\u677f\u5242\u7b49\uff0c\u5b83\u90fd\u53d1\u6325\u7740\u91cd\u8981\u4f5c\u7528\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

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